Novel Sustained-Release Drug Delivery System for Dry Eye Therapy by Rebamipide Nanoparticles

• Main Authors: Noriaki Nagai (Author), Miyu Ishii (Author), Ryotaro Seiriki (Author), Fumihiko Ogata (Author), Hiroko Otake (Author), Yosuke Nakazawa (Author), Norio Okamoto (Author), Kazutaka Kanai (Author), Naohito Kawasaki (Author)
• Format: Book
• Published: MDPI AG, 2020-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The commercially available rebamipide ophthalmic suspension (CA-REB) was approved for clinical use in patients with dry eye; however, the residence time on the ocular surface for the traditional formulations is short, since the drug is removed from the ocular surface through the nasolacrimal duct. I...