Deconstructing Markush: Improving the R&D Efficiency Using Library Selection in Early Drug Discovery
Most of the product patents claim a large number of compounds based on a Markush structure. However, the identification and optimization of new principal active ingredients is frequently driven by a simple Free Wilson approach, leading to a highly focused study only involving the chemical space near...
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| Main Authors: | , , , |
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| Format: | Book |
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MDPI AG,
2022-09-01T00:00:00Z.
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Internet
Connect to this object online.3rd Floor Main Library
| Call Number: |
A1234.567 |
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| Copy 1 | Available |