Changes in peripheral mitochondrial DNA copy number in metformin-treated women with polycystic ovary syndrome: a longitudinal study

• Autori principali: Po-Kai Yang (Autore), Chia-Hong Chou (Autore), Chin-Hao Chang (Autore), Shee-Uan Chen (Autore), Hong-Nerng Ho (Autore), Mei-Jou Chen (Autore)
• Natura: Libro
• Pubblicazione: BMC, 2020-07-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Abstract Background Patients with polycystic ovarian syndrome (PCOS) are associated with known alterations in mitochondria DNA copy number (mtDNA-CN). The aim of this study is to study the change in mtDNA-CN in patients with PCOS who were treated with metformin. Methods This is a prospective cohort...