Modulating the RFamide-related peptide-3/G protein-coupled receptor 147 signaling pathway with nourishing Yin-removing fire herbal mixture to alleviate precocious puberty in female rats: An experimental study

• Main Authors: Xiaoli Dai (Author), Yuanyuan He (Author), Suhuan Li (Author), Yanyan Sun (Author), Wen Sun (Author), Zhanzhuang Tian (Author), Ph.D (Author), Jian Yu (Author), Nurgul Ablakimova (Author), Yonghong Wang (Author)
• Format: Book
• Published: Shahid Sadoughi University of Medical Sciences, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background: Precocious puberty (PP) involves early activation of the hypothalamic gonadotropin-releasing hormone (GnRH) generator. The RFamide-related peptide/G protein-coupled receptor 147 (RFRP3/GPR147) signaling pathway is vital in inhibiting GnRH and delaying puberty onset. The nourishi...