Spatial expression of the FGFR2b splice isoform and its prognostic significance in endometrioid endometrial carcinoma

• Main Authors: Asmerom T Sengal (Author), Deborah Smith (Author), Cameron E Snell (Author), Samuel Leung (Author), Aline Talhouk (Author), Elizabeth D Williams (Author), Jessica N McAlpine (Author), Pamela M Pollock (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Endometrial carcinoma (EC) is the most common gynecological malignancy and fibroblast growth factor receptor 2 (FGFR2) is a frequently dysregulated receptor tyrosine kinase. FGFR2b and FGFR2c are the two main splice isoforms of FGFR2 and are normally localized in epithelial and mesenchymal...