Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System

• Egile Nagusiak: Amanda E. I. Proudfoot (Egilea), Zoë Johnson (Egilea), Pauline Bonvin (Egilea), Tracy M. Handel (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2017-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Chemokines have two types of interactions that function cooperatively to control cell migration. Chemokine receptors on migrating cells integrate signals initiated upon chemokine binding to promote cell movement. Interactions with glycosaminoglycans (GAGs) localize chemokines on and near cell surfac...