Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-OTS) in Sprague Dawley Rats

• Main Authors: Chen Ankri (Author), Oren Hershkovitz (Author), Liat Hershkovitz (Author), Meital Brami (Author), Ronnie Levy (Author), Hadar Sarig (Author), Einat Souli (Author), Barak Reicher (Author), Veronique Amor-Baroukh (Author), Dror Mevorach (Author), Abraham Nyska (Author)
• Format: Book
• Published: MDPI AG, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed in a GLP toxicological study on Sprague Dawley rat...