GSDMD in peripheral myeloid cells regulates microglial immune training and neuroinflammation in Parkinson's disease

• Main Authors: Bingwei Wang (Author), Yan Ma (Author), Sheng Li (Author), Hang Yao (Author), Mingna Gu (Author), Ying Liu (Author), You Xue (Author), Jianhua Ding (Author), Chunmei Ma (Author), Shuo Yang (Author), Gang Hu (Author)
• Format: Book
• Published: Elsevier, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peripheral bacterial infections without impaired blood-brain barrier integrity have been attributed to the pathogenesis of Parkinson's disease (PD). Peripheral infection promotes innate immune training in microglia and exacerbates neuroinflammation. However, how changes in the peripheral enviro...