Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease

Potential Role of Methotrexate Polyglutamates in Therapeutic Drug Monitoring for Pediatric Inflammatory Bowel Disease

Inside cells, the immunomodulator methotrexate (MTX) undergoes the addition of glutamates to form methotrexate polyglutamates (MTX-Glu)-promising biomarkers of systemic exposure and treatment response to MTX in rheumatology. MTX-Glu are underexplored in Inflammatory Bowel Disease (IBD), with no data...

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Main Authors: Ryan Morrow (Author), Ryan Funk (Author), Mara Becker (Author), Ashley Sherman (Author), Leon Van Haandel (Author), Taina Hudson (Author), Rebecca Casini (Author), Valentina Shakhnovich (Author)
Format: Book
Published: MDPI AG, 2021-05-01T00:00:00Z.
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3rd Floor Main Library

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