Apolipoprotein C3 and circulating mediators of preadipocyte proliferation in states of lipodystrophy

• Main Authors: Brandao Bruna Brasil (Author), Sakaguchi Masaji (Author), Batista, Thiago Martins (Author), Hu Jiang (Author), Nie Song (Author), Schepmoes Athena A (Author), BonDurant Lucas (Author), Moreau François (Author), Qian Wei-Jun (Author), Kulkarni N. Rohit (Author), Kahn, C. Ronald (Author)
• Format: Book
• Published: Elsevier, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adipogenesis is a complex process controlled by intrinsic and extrinsic factors that regulate preadipocyte proliferation, adipogenic capacity and maturation of metabolic function. Here we show that insulin and IGF-1 receptors are essential for mature adipocyte survival and that deletion of both IR a...