A DNA-based nanocarrier for efficient cancer therapy

• Main Authors: Muhammad Abbas (Author), Mirza Muhammad Faran Ashraf Baig (Author), Yaliang Zhang (Author), Yu-Shun Yang (Author), Songyu Wu (Author), Yiqiao Hu (Author), Zhong-Chang Wang (Author), Hai-Liang Zhu (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study aimed to achieve enhanced targeted cytotoxicity and cell-internalization of cisplatin-loaded deoxyribonucleic acid-nanothread (CPT-DNA-NT), mediated by scavenger receptors into HeLa cells. DNA-NT was developed with stiff-topology utilizing circular-scaffold to encapsulate CPT. Atomic force...