Rift valley Fever virus encephalitis is associated with an ineffective systemic immune response and activated T cell infiltration into the CNS in an immunocompetent mouse model.

• Main Authors: Kimberly A Dodd (Author), Anita K McElroy (Author), Tara L Jones (Author), Sherif R Zaki (Author), Stuart T Nichol (Author), Christina F Spiropoulou (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rift Valley fever virus (RVFV) causes outbreaks of severe disease in livestock and humans throughout Africa and the Arabian Peninsula. In people, RVFV generally causes a self-limiting febrile illness but in a subset of individuals, it progresses to more serious disease. One manifestation is a delaye...