Comparative pharmacokinetics of polymyxin B in critically ill elderly patients with extensively drug-resistant gram-negative bacteria infections

• 主要な著者: Juan Zeng (著者), Bing Leng (著者), Xiaoyan Guan (著者), Shuangyan Jiang (著者), Maoyu Xie (著者), Wenying Zhu (著者), Yue Tang (著者), Lin Zhang (著者), Jing Sha (著者), Tengfei Wang (著者), Min Ding (著者), Nan Guo (著者), Jinjiao Jiang (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Introduction: Elderly patients are more prone to develop acute kidney injury during infections and polymyxin B (PMB)-associated nephrotoxicity than young patients. The differential response to PMB between the elderly and young critically ill patients is unknown. We aimed to assess PMB exposure in el...