Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice

• Hoofdauteurs: Lei Wang (Auteur), Sai P. Pydi (Auteur), Yinghong Cui (Auteur), Lu Zhu (Auteur), Jaroslawna Meister (Auteur), Oksana Gavrilova (Auteur), Rebecca Berdeaux (Auteur), Jean-Philippe Fortin (Auteur), Kendra K. Bence (Auteur), Cecile Vernochet (Auteur), Jürgen Wess (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Objective: Given the worldwide epidemics of obesity and type 2 diabetes, novel antidiabetic and appetite-suppressing drugs are urgently needed. Adipocytes play a central role in the regulation of whole-body glucose and energy homeostasis. The goal of this study was to examine the metabolic effects o...