Tumor Microenvironment-Responsive Polymeric iRGD and Doxorubicin Conjugates Reduce Spontaneous Lung Metastasis in an Orthotopic Breast Cancer Model

• Main Authors: Zheng-Hong Peng (Author), Chinmay M. Jogdeo (Author), Jing Li (Author), Ying Xie (Author), Yazhe Wang (Author), Yuri M. Sheinin (Author), Jindřich Kopeček (Author), David Oupický (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tremendous progress has been made in the field of nanomedicine for cancer treatment. However, most of the research to date has been focused on inhibiting primary tumor growth with comparatively less efforts directed towards managing tumor metastasis. Here, we introduce a polymeric conjugate P-DOX-iR...