Prospects for the Development of Pink1 and Parkin Activators for the Treatment of Parkinson's Disease

• Main Authors: Alexander V. Blagov (Author), Andrey G. Goncharov (Author), Olga O. Babich (Author), Viktoriya V. Larina (Author), Alexander N. Orekhov (Author), Alexandra A. Melnichenko (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2022-11-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Impaired mitophagy is one of the hallmarks of the pathogenesis of Parkinson's disease, which highlights the importance of the proper functioning of mitochondria, as well as the processes of mitochondrial dynamics for the functioning of dopaminergic neurons. At the same time, the main factors le...