Sorbitol Destroyed Intestinal Microfold Cells (M Cells) Development through Inhibition of PDE4-Mediated RANKL Expression

• Main Authors: Li Xiang (Author), Wenxu Pan (Author), Huan Chen (Author), Wenjun Du (Author), Shuping Xie (Author), Xinhua Liang (Author), Fangying Yang (Author), Rongwei Niu (Author), Canxin Huang (Author), Minan Luo (Author), Yuxin Xu (Author), Lanlan Geng (Author), Sitang Gong (Author), Wanfu Xu (Author), Junhong Zhao (Author)
• Format: Book
• Published: Hindawi Limited, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective. Microfold cells (M cells) are specific intestinal epithelial cells for monitoring and transcytosis of antigens, microorganisms, and pathogens in the intestine. However, the mechanism for M-cell development remained elusive. Materials and Methods. Real-time polymerase chain reaction, immun...