Pharmacogenomics Factors Influencing the Effect of Risperidone on Prolactin Levels in Thai Pediatric Patients With Autism Spectrum Disorder

• Main Authors: Yaowaluck Hongkaew (Author), Andrea Gaedigk (Author), Bob Wilffert (Author), Roger Gaedigk (Author), Wiranpat Kittitharaphan (Author), Nattawat Ngamsamut (Author), Penkhae Limsila (Author), Apichaya Puangpetch (Author), Rattanaporn Sukprasong (Author), Chonlaphat Sukasem (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the association between genetic variations in pharmacodynamic genes and risperidone-induced increased prolactin levels in children and adolescents with autism spectrum disorder (ASD). In a retrospective study, variants of pharmacodynamic genes were analyzed in 124 ASD patients treate...