Extrahepatic cytochrome P450s play an insignificant role in triptolide-induced toxicity

Abstract Background Triptolide, an active ingredient of Chinese medicine plant Tripterygium wilfordii Hook.f., has been shown to exert anti-tumor, immunosuppressive, anti-inflammatory, and anti-fertility pharmacological effects. However, triptolide also causes severe side effects, which are manifest...

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Main Authors: Yuan Wei (Author), Dujun Wang (Author), Meng Chen (Author), Zhen Ouyang (Author), Shuo Wang (Author), Jun Gu (Author)
Format: Book
Published: BMC, 2018-04-01T00:00:00Z.
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3rd Floor Main Library

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