Pharmacokinetic and Metabolic Profile of Deutetrabenazine (TEV‐50717) Compared With Tetrabenazine in Healthy Volunteers

• Main Authors: Frank Schneider (Author), Margaret Bradbury (Author), Thomas A. Baillie (Author), David Stamler (Author), Edward Hellriegel (Author), Donna S. Cox (Author), Pippa S. Loupe (Author), Juha‐Matti Savola (Author), Laura Rabinovich‐Guilatt (Author)
• Format: Book
• Published: Wiley, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deutetrabenazine (Austedo, Teva Pharmaceuticals) is a deuterated form of tetrabenazine. It is the first deuterated drug to receive US regulatory approval and is approved for treatment of chorea in Huntington's disease and tardive dyskinesia. Two oral single dose studies comparing deutetrabenazi...