Parthenolide ameliorates 3-nitropropionic acid-induced Huntington's disease-like aberrations via modulating NLRP3 inflammasome, reducing microglial activation and inducing astrocyte shifting

• Asıl Yazarlar: Mona E. Noureldeen (Yazar), Nancy N. Shahin (Yazar), Hebat Allah A. Amin (Yazar), Maha M. El-Sawalhi (Yazar), Heba R. Ghaiad (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2024-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Huntington's disease (HD) is a progressive neurodegenerative disease that causes motor, cognitive, and psychiatric abnormalities, with no satisfying disease-modifying therapy so far. 3-nitropropionic acid (3NP) induces behavioural deficits, together with biochemical and hist...