Heme oxygenase 1 polymorphism, occupational vapor, gas, dust, and fume exposure and chronic obstructive pulmonary disease in a Danish population-based study

• Main Authors: Else Toft Würtz (Author), Charlotte Brasch-Andersen (Author), Rudi Steffensen (Author), Jens Georg Hansen (Author), Tine Halsen Malling (Author), Vivi Schlünssen (Author), Øyvind Omland (Author)
• Format: Book
• Published: Nordic Association of Occupational Safety and Health (NOROSH), 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

OBJECTIVES: The number of dinucleotide repeats (GT)_n modulate expression of heme oxygenase 1 (HMOX1), a stress response gene. Multiple repeats might affect chronic obstructive pulmonary disease (COPD) susceptibility. We aimed to investigate the association of this polymorphism with COPD and its int...