Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination which may hamper drug efficacy in sleeping sickness.
Monitoring Trypanosoma spread using real-time imaging in vivo provides a fast method to evaluate parasite distribution especially in immunoprivileged locations. Here, we generated monomorphic and pleomorphic recombinant Trypanosoma brucei expressing the Renilla luciferase. In vitro luciferase activi...
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Main Authors: | Filip Claes (Author), Suman K Vodnala (Author), Nick van Reet (Author), Nathalie Boucher (Author), Hilda Lunden-Miguel (Author), Theo Baltz (Author), Bruno Maria Goddeeris (Author), Philippe Büscher (Author), Martin E Rottenberg (Author) |
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Format: | Book |
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Public Library of Science (PLoS),
2009-01-01T00:00:00Z.
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