CXCR3 chemokine receptor guides Trypanosoma cruzi-specific T-cells triggered by DNA/adenovirus ASP2 vaccine to heart tissue after challenge.

• Main Authors: Camila Pontes Ferreira (Author), Leonardo Moro Cariste (Author), Barbara Ferri Moraschi (Author), Bianca Ferrarini Zanetti (Author), Sang Won Han (Author), Daniel Araki Ribeiro (Author), Alexandre Vieira Machado (Author), Joseli Lannes-Vieira (Author), Ricardo Tostes Gazzinelli (Author), José Ronnie Carvalho Vasconcelos (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD8+ T lymphocytes play an important role in controlling infections by intracellular pathogens. Chemokines and their receptors are crucial for the migration of CD8+ T-lymphocytes, which are the main IFNγ producers and cytotoxic effectors cells. Although the participation of chemokine ligands and rec...