Next generation sequencing in clinical medicine: Challenges and lessons for pathology and biomedical informatics

• Main Authors: Rama R Gullapalli (Author), Ketaki V Desai (Author), Lucas Santana-Santos (Author), Jeffrey A Kant (Author), Michael J Becich (Author)
• Format: Book
• Published: Elsevier, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Human Genome Project (HGP) provided the initial draft of mankind's DNA sequence in 2001. The HGP was produced by 23 collaborating laboratories using Sanger sequencing of mapped regions as well as shotgun sequencing techniques in a process that occupied 13 years at a cost of ~$3 billion. Tod...