A Randomized Controlled Dose-Escalation Study of LY06006, a Recombinant Humanized Monoclonal Antibody to RANKL, in Chinese Healthy Adults

• Main Authors: Suping Niu (Author), Min Chen (Author), Diqin Yan (Author), Xiangxing Liu (Author), Shuren Guo (Author), Lun Ou (Author), Huaying Fan (Author), Jie Lv (Author), Qian Wang (Author), Wenliang Dong (Author), Lin Xia (Author), Simin Wang (Author), Gang Liu (Author), Qun Gu (Author), Danjie Guo (Author), Hongxia Liu (Author), Huiying Rao (Author), Qingshan Zheng (Author), Xiaoyan Nie (Author), Haifeng Song (Author), Yi Fang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: This study was conducted to explore the safety, tolerance, pharmacokinetics, pharmacodynamics, and immunogenicity of LY06006, a recombinant humanized monoclonal antibody to RANKL, when administrated subcutaneously in Chinese healthy adults.Research design and methods: This was a randomiz...