Microspheres prepared with biodegradable PHBV and PLA polymers as prolonged-release system for ibuprofen: in vitro drug release and in vivo evaluation
In this study, poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV) and poly(l-lactide) (PLA) microspheres containing ibuprofen were prepared with the aim of prolonging the drug release. The oil-in-water (O/W) emulsion solvent evaporation technique was used, varying the polymer ratio. All formulations pr...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Universidade de São Paulo,
2012-12-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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