Inhibitory Effects of Auraptene and Naringin on Astroglial Activation, Tau Hyperphosphorylation, and Suppression of Neurogenesis in the Hippocampus of Streptozotocin-Induced Hyperglycemic Mice

• Main Authors: Satoshi Okuyama (Author), Tatsumi Nakashima (Author), Kumi Nakamura (Author), Wakana Shinoka (Author), Maho Kotani (Author), Atsushi Sawamoto (Author), Mitsunari Nakajima (Author), Yoshiko Furukawa (Author)
• Format: Book
• Published: MDPI AG, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Auraptene, a citrus-related compound, exerts anti-inflammatory effects in peripheral tissues, and we demonstrated these effects in the brains of a lipopolysaccharide-injected systemic inflammation animal model and a brain ischemic mouse model. Naringin, another citrus-related compound, has been show...