HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression

• Main Authors: Frincke James M (Author), White Steven K (Author), van Heeckeren Anna M (Author), Mangano Katia (Author), Nicoletti Ferdinando (Author), Pieters Raymond (Author), Wang Angela (Author), Conrad Douglas (Author), Reading Christopher L (Author), Stickney Dwight (Author), Auci Dominick L (Author)
• Format: Book
• Published: BMC, 2010-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>17α-Ethynyl-5-androsten-3β, 7β, 17β-triol (HE3286) is a synthetic derivative of an endogenous steroid androstenetriol (β-AET), a metabolite of the abundant adrenal steroid deyhdroepiandrosterone (DHEA), with broad anti-inflammatory a...