Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo

• Principais autores: Tao Su (Autor), Xia Yang (Autor), Jian-Hua Deng (Autor), Qiu-Ju Huang (Autor), Su-Chao Huang (Autor), Yan-Min Zhang (Autor), Hong-Ming Zheng (Autor), Ying Wang (Autor), Lin-Lin Lu (Autor), Zhong-Qiu Liu (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Lung cancer is a leading cause of cancer-related deaths worldwide. NOTCH3 signaling is mainly expressed in non-small cell lung carcinoma (NSCLC), and has been proposed as a therapeutic target of NSCLC. While, few agents for preventing or treating NSCLC via targeting NOTCH3 signaling are used in mode...