Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo

• Main Authors: Tao Su (Author), Xia Yang (Author), Jian-Hua Deng (Author), Qiu-Ju Huang (Author), Su-Chao Huang (Author), Yan-Min Zhang (Author), Hong-Ming Zheng (Author), Ying Wang (Author), Lin-Lin Lu (Author), Zhong-Qiu Liu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lung cancer is a leading cause of cancer-related deaths worldwide. NOTCH3 signaling is mainly expressed in non-small cell lung carcinoma (NSCLC), and has been proposed as a therapeutic target of NSCLC. While, few agents for preventing or treating NSCLC via targeting NOTCH3 signaling are used in mode...