Novel polyethyleneimine-R8-heparin nanogel for high-efficiency gene delivery in vitro and in vivo

• Main Authors: Linjiang Song (Author), Xiuqi Liang (Author), Suleixin Yang (Author), Ning Wang (Author), Tao He (Author), Yan Wang (Author), Lan Zhang (Author), Qinjie Wu (Author), Changyang Gong (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gene therapy is an efficient and promising approach to treat malignant tumors. However, protecting the nucleic acid from degradation in vivo and efficient delivering it into tumor cells remain challenges that require to be addressed before gene therapy could be applied in clinic. In this study, we p...