Distribution, excretion and metabolic pathways of a single parenteral administration of kappa-opioid receptor agonist RU-1205

• Главные авторы: Alexander A. Spasov (Автор), Lyudmila A. Smirnova (Автор), Olesya Iu. Grechko (Автор), Natalya V. Eliseeva (Автор), Yuliya V. Lifanova (Автор), Andrey I. Rashchenko (Автор), Olga N. Zhukowskaia (Автор), Anatoly S. Morkovnik (Автор), Vera A. Anisimova (Автор), Olga E. Syrvacheva (Автор)
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• Опубликовано: Belgorod National Research University, 2021-06-01T00:00:00Z.
• Предметы: article
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Introduction: The purpose was to study the pharmacokinetic properties of RU-1205 with the previously identified kappa-agonistic and analgesic effects after parenteral administration. Materials and methods: Pharmacokinetic parameters of RU-1205 after intravenous and subcutaneous administration at dos...