Distribution, excretion and metabolic pathways of a single parenteral administration of kappa-opioid receptor agonist RU-1205

• Main Authors: Alexander A. Spasov (Author), Lyudmila A. Smirnova (Author), Olesya Iu. Grechko (Author), Natalya V. Eliseeva (Author), Yuliya V. Lifanova (Author), Andrey I. Rashchenko (Author), Olga N. Zhukowskaia (Author), Anatoly S. Morkovnik (Author), Vera A. Anisimova (Author), Olga E. Syrvacheva (Author)
• Format: Book
• Published: Belgorod National Research University, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: The purpose was to study the pharmacokinetic properties of RU-1205 with the previously identified kappa-agonistic and analgesic effects after parenteral administration. Materials and methods: Pharmacokinetic parameters of RU-1205 after intravenous and subcutaneous administration at dos...