Factor VII-Induced MicroRNA-135a Inhibits Autophagy and Is Associated with Poor Prognosis in Hepatocellular Carcinoma

• Main Authors: Kuang-Tzu Huang (Author), I-Ying Kuo (Author), Ming-Chao Tsai (Author), Chun-Hsien Wu (Author), Li-Wen Hsu (Author), Li-Yu Chen (Author), Chao-Pin Kung (Author), Yu-Fan Cheng (Author), Shigeru Goto (Author), Yu-Wei Chou (Author), Chao-Long Chen (Author), Chih-Che Lin (Author), Kuang-Den Chen (Author)
• Format: Book
• Published: Elsevier, 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Hepatocellular carcinoma (HCC) is one of the most common and aggressive malignancies worldwide. Treatment outcomes remain poor mainly due to lack of good diagnostic/prognostic markers and limited therapeutic strategies. We previously characterized aberrant activation of the TF/FVII/PAR2 pathway, whi...