Analysis of clinically-reported, memantine-induced cardiovascular adverse responses using the halothane-anesthetized dogs: Reverse translational study

• Main Authors: Ryuichi Kambayashi (Author), Ai Goto (Author), Mihoko Hagiwara-Nagasawa (Author), Hiroko Izumi-Nakaseko (Author), Makoto Shinozaki (Author), Shinichi Kawai (Author), Akio Matsumoto (Author), Yoshinori Takei (Author), Atsushi Sugiyama (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Although NMDA receptor antagonist memantine is considered to be better tolerated than cholinesterase inhibitors on treating Alzheimer's disease, several types of cardiovascular adverse events have been associated with memantine treatment, including hypertension, myocardial infarction, severe br...