Neutralizing antibody response elicited by SARS-CoV-2 receptor-binding domain

• Main Authors: Ping-Han Huang (Author), Hsiao-Han Tsai (Author), Bo-Hung Liao (Author), Yi-Ling Lin (Author), Jia-Tsrong Jan (Author), Mi-Hua Tao (Author), Yu-Chi Chou (Author), Che-Ming Jack Hu (Author), Hui-Wen Chen (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A safe and effective vaccine candidate is urgently needed for the ongoing COVID-19 pandemic, caused by SARS-CoV-2. Here we report that recombinant SARS-CoV-2 RBD protein immunization in mice is able to elicit a strong antibody response and potent neutralizing capability as measured using live or pse...