Recent Advances in Cancer Drug Discovery Through the Use of Phenotypic Reporter Systems, Connectivity Mapping, and Pooled CRISPR Screening

Multi-omic approaches offer an unprecedented overview of the development, plasticity, and resistance of cancer. However, the translation from anti-cancer compounds identified in vitro to clinically active drugs have a notoriously low success rate. Here, we review how technical advances in cell cultu...

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Main Authors: Natasha Salame (Author), Katharine Fooks (Author), Nehme El-Hachem (Author), Jean-Pierre Bikorimana (Author), François E. Mercier (Author), Moutih Rafei (Author)
Format: Book
Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
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3rd Floor Main Library

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