Monozygotic Twins Discordant for Immunoglobulin A Nephropathy Display Differences in DNA Methylation and Gene Expression

• Hlavní autoři: Min Wei (Autor), Sijun Meng (Autor), Sufang Shi (Autor), Lijun Liu (Autor), Xujie Zhou (Autor), Jicheng Lv (Autor), Li Zhu (Autor), Hong Zhang (Autor)
• Médium: Kniha
• Vydáno: Karger Publishers, 2020-12-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Introduction: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis. It involves both genetic and environmental factors, among which DNA methylation, the most studied epigenetic modification, was shown to play a role. Here, we assessed genome-wide DNA methylation and gene...