Monozygotic Twins Discordant for Immunoglobulin A Nephropathy Display Differences in DNA Methylation and Gene Expression

• Main Authors: Min Wei (Author), Sijun Meng (Author), Sufang Shi (Author), Lijun Liu (Author), Xujie Zhou (Author), Jicheng Lv (Author), Li Zhu (Author), Hong Zhang (Author)
• Format: Book
• Published: Karger Publishers, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis. It involves both genetic and environmental factors, among which DNA methylation, the most studied epigenetic modification, was shown to play a role. Here, we assessed genome-wide DNA methylation and gene...