Monozygotic Twins Discordant for Immunoglobulin A Nephropathy Display Differences in DNA Methylation and Gene Expression

• Prif Awduron: Min Wei (Awdur), Sijun Meng (Awdur), Sufang Shi (Awdur), Lijun Liu (Awdur), Xujie Zhou (Awdur), Jicheng Lv (Awdur), Li Zhu (Awdur), Hong Zhang (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Karger Publishers, 2020-12-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Introduction: Immunoglobulin A nephropathy (IgAN) is the most common primary glomerulonephritis. It involves both genetic and environmental factors, among which DNA methylation, the most studied epigenetic modification, was shown to play a role. Here, we assessed genome-wide DNA methylation and gene...