Targeted next generation sequencing identifies a genetic spectrum of DNA variants in patients with hemiplegic migraine

• Main Authors: Neven Maksemous (Author), Robert A Smith (Author), Heidi G Sutherland (Author), Bridget H Maher (Author), Omar Ibrahim (Author), Garth A Nicholson (Author), Elisabeth P Carpenter (Author), Rod A Lea (Author), M Zameel Cader (Author), Lyn R Griffiths (Author)
• Format: Book
• Published: SAGE Publishing, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Hemiplegic migraine in both familial (FHM) and sporadic (SHM) forms is a rare subtype of migraine with aura that can be traced to mutations in the CACNA1A , ATP1A2 and SCN1A genes. It is characterised by severe attacks of typical migraine accompanied by hemiparesis, as well as episodes of...