Pharmacokinetics and Quantitative Structure-Pharmacokinetics Relationship Study of Xanthine Derivatives with Antidepressant, Anti-Inflammatory, and Analgesic Activity in Rats

Pharmacokinetics and Quantitative Structure-Pharmacokinetics Relationship Study of Xanthine Derivatives with Antidepressant, Anti-Inflammatory, and Analgesic Activity in Rats

Objective: The aim of this study was to develop quantitative structure-pharmacokinetics relationship (QSPKR) models for a group of xanthine derivatives with proven pharmacological activity and to investigate its applicability for the prediction of the pharmacokinetics of these compounds. Methods: Th...

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Main Authors: Artur Świerczek (Author), Małgorzata Szafarz (Author), Agnieszka Cios (Author), Jan Kobierski (Author), Krzysztof Pociecha (Author), Daniel Attard Saliba (Author), Grażyna Chłoń-Rzepa (Author), Elżbieta Wyska (Author)
Format: Book
Published: MDPI AG, 2024-11-01T00:00:00Z.
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