Carvacrol inhibits the neuronal voltage-gated sodium channels Nav1.2, Nav1.6, Nav1.3, Nav1.7, and Nav1.8 expressed in Xenopus oocytes with different potencies

• Автори: Takafumi Horishita (Автор), Yuichi Ogata (Автор), Reiko Horishita (Автор), Ryo Fukui (Автор), Kuniaki Moriwaki (Автор), Susumu Ueno (Автор), Nobuyuki Yanagihara (Автор), Yasuhito Uezono (Автор), Yuka Sudo (Автор), Kouichiro Minami (Автор)
• Формат: Книга
• Опубліковано: Elsevier, 2020-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Carvacrol is the predominant monoterpene in essential oils from many aromatic plants. Several animal studies showing analgesic effects of carvacrol indicate potential of carvacrol as a new medication for patients with refractory pain. Voltage-gated sodium channels (Nav) are thought to have crucial r...