Effect of Lipid Composition on the Atheroprotective Properties of HDL-Mimicking Micelles

• Main Authors: Kristen Hong (Author), Minzhi Yu (Author), Julia Crowther (Author), Ling Mei (Author), Karl Olsen (Author), Yonghong Luo (Author), Yuqing Eugene Chen (Author), Yanhong Guo (Author), Anna Schwendeman (Author)
• Format: Book
• Published: MDPI AG, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atherosclerosis progression is driven by an imbalance of cholesterol and unresolved local inflammation in the arteries. The administration of recombinant apolipoprotein A-I (ApoA-I)-based high-density lipoprotein (HDL) nanoparticles has been used to reduce the size of atheroma and rescue inflammator...