Broadening our understanding of genetic risk for scleroderma/systemic sclerosis by querying the chromatin architecture surrounding the risk haplotypes

• 主要な著者: Kerry E. Poppenberg (著者), Vincent M. Tutino (著者), Evan Tarbell (著者), James N. Jarvis (著者)
• フォーマット: 図書
• 出版事項: BMC, 2021-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Abstract Background Genetic variants in the human leukocyte antigen (HLA) locus contribute to the risk for developing scleroderma/systemic sclerosis (SSc). However, there are other replicated loci that also contribute to genetic risk for SSc, and it is unknown whether genetic risk in these non-HLA l...