Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics

• Κύριοι συγγραφείς: Xing Lin (Συγγραφέας), Yuanyuan Wei (Συγγραφέας), Yan Li (Συγγραφέας), Yuhua Xiong (Συγγραφέας), Bin Fang (Συγγραφέας), Cuiyu Li (Συγγραφέας), Quanfang Huang (Συγγραφέας), Renbin Huang (Συγγραφέας), Jinbin Wei (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

This study aimed to investigate the effects and underlying mechanisms of tormentic acid (TA) on carbon tetrachloride (CCl4)-induced liver fibrosis in rats. The rats were intragastrically administered with 50% CCl4 for 9 weeks to induce hepatic fibrosis, followed by various agents for 6 weeks. Transc...