Involvement of HDAC1 and HDAC3 in the Pathology of Polyglutamine Disorders: Therapeutic Implications for Selective HDAC1/HDAC3 Inhibitors

• מחבר ראשי: Elizabeth A. Thomas (Author)
• פורמט: ספר
• יצא לאור: MDPI AG, 2014-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Histone deacetylases (HDACs) enzymes, which affect the acetylation status of histones and other important cellular proteins, have been recognized as potentially useful therapeutic targets for a broad range of human disorders. Emerging studies have demonstrated that different types of HDAC inhibitors...