Targeting of temozolomide using magnetic nanobeads: an in vitro study

• Main Authors: Berna Gürten (Author), Elçin Yenigül (Author), Ali Demir Sezer (Author), Cem Altan (Author), Seyda Malta (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Temozolomide, a chemotherapeutic drug that is often administered for the treatment of brain cancer has severe side effects and a poor aqueous solubility. In order to decrease the detrimental effect of the drug over healthy cells, a novel drug delivery vehicle was developed where the therapeutic drug...