In Silico Exploration of Novel EGFR Kinase Mutant-Selective Inhibitors Using a Hybrid Computational Approach

• Main Authors: Md Ali Asif Noor (Author), Md Mazedul Haq (Author), Md Arifur Rahman Chowdhury (Author), Hilal Tayara (Author), HyunJoo Shim (Author), Kil To Chong (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Targeting epidermal growth factor receptor (EGFR) mutants is a promising strategy for treating non-small cell lung cancer (NSCLC). This study focused on the computational identification and characterization of potential EGFR mutant-selective inhibitors using pharmacophore design and validation by de...