In Silico Exploration of Novel EGFR Kinase Mutant-Selective Inhibitors Using a Hybrid Computational Approach

• Glavni autori: Md Ali Asif Noor (Autor), Md Mazedul Haq (Autor), Md Arifur Rahman Chowdhury (Autor), Hilal Tayara (Autor), HyunJoo Shim (Autor), Kil To Chong (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2024-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Targeting epidermal growth factor receptor (EGFR) mutants is a promising strategy for treating non-small cell lung cancer (NSCLC). This study focused on the computational identification and characterization of potential EGFR mutant-selective inhibitors using pharmacophore design and validation by de...