Development of a Microwave-assisted Chemoselective Synthesis of Oxime-linked Sugar Linkers and Trivalent Glycoclusters

• Hauptverfasser: Katherine McReynolds (Verfasst von), Dustin Dimas (Verfasst von), Grace Floyd (Verfasst von), Kara Zeman (Verfasst von)
• Format: Buch
• Veröffentlicht: MDPI AG, 2019-03-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

A rapid, high-yielding microwave-mediated synthetic procedure was developed and optimized using a model system of monovalent sugar linkers, with the ultimate goal of using this method for the synthesis of multivalent glycoclusters. The reaction occurs between the aldehyde/ketone on the sugars and an...