OMV-based vaccine formulations against Shiga toxin producing Escherichia coli strains are both protective in mice and immunogenic in calves

OMV-based vaccine formulations against Shiga toxin producing Escherichia coli strains are both protective in mice and immunogenic in calves

Strains of Shiga toxin-producing Escherichia coli (STEC) can cause the severe Hemolytic Uremic Syndrome (HUS). Shiga toxins are protein toxins that bind and kill microvascular cells, damaging vital organs. No specific therapeutics or vaccines have been licensed for use in humans yet. The most common...

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Main Authors: Matias Fingermann (Author), Lucía Avila (Author), Maria Belén De Marco (Author), Luciana Vázquez (Author), Darío Nicolás Di Biase (Author), Andrea Verónica Müller (Author), Mirta Lescano (Author), José Christian Dokmetjian (Author), Sonsire Fernández Castillo (Author), José Luis Pérez Quiñoy (Author)
Format: Book
Published: Taylor & Francis Group, 2018-09-01T00:00:00Z.
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